Welcome to the SANTAGATA LAB!

We identify and target vulnerabilities in tumors to improve patient outcome and survival, focusing on primary brain tumors and tumors that metastasize to the brain.

Through genomics, chemical biology, and multiplexed imaging we explore the fundamental mechanisms that allow tumor cells to develop their most malignant features along with our colleagues in the Lab for Systems Pharmacology and the Ludwig Center at Harvard.

As experimental pathologists in the Department of Pathology at Brigham and Women’s Hospital (Brigham Health), we routinely move from model systems to primary human tumor tissues and back. Please see our News Stream and our Publications List for our latest contributions.